Humbled by Possibility

Bloom Science is a platform biotechnology company discovering and developing revolutionary new drugs targeting the gut-brain axis for the treatment and modification of diseases with high unmet need in neurology, immunology and oncology.

our mission
1

Re-imagine better solutions for patients.

2

Make measurable improvements to outcomes.

3

Deliver these solutions to patients in a timeframe that matters.

hacking the gut brain axis to identify novel therapeutics

You’re more microbe than human – if you count all the cells in your body, only 43% are human.

Our proprietary platform developed by Bloom’s scientific co-founder Elaine Hsiao, PhD (UCLA) leverages genomic, gut microbiome, metabolomic and data analytics knowledge bases in combination with phenotypic screening to discover novel targets focused on the gut-brain axis and deliver the next generation of targeted therapeutics in areas with a clear path to deliver clinical innovation.

The Ketogenic Diet
The ketogenic diet has been effectively used to treat refractory epilepsy and rare orphan epilepsy syndromes since the 1920's.
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The Gut Microbiome
The gut is home to trillions of microorganisms that digest our food, educate our immune systems, control our metabolism and influence our brains. The ketogenic diet can alter the types and functions of microbes in the gut in ways that influence the nervous system.
The Gut-Brain Axis
Alterations in the microbial communities that inhabit us are implicated in a variety of neurological disorders, including epilepsy, autism, anxiety and Parkinson’s disease.

Microbial dietary metabolism regulates secondary metabolites that in turn influence neuronal function.
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Seizure Protection
In preclinical studies, our data reveal a novel role specific bacteria play in providing seizure protection in epilepsy models and adds to our understanding of the important function our microbiome serves in modulating brain activity.

Our approach is to leverage  naturally-occurring microbes that modulate neuroactive molecules in our brain to discover new therapeutic opportunities.

Bloom Science co-founder Dr. Elaine Hsiao provides overview of how the microbiome affects brain and behavior.

PATIENTS and CAREGIVERS

We seek to empower patients and families by bringing hope for conditions where there are few treatment options.

It is our responsibility to seek innovation, to understand the challenges faced by patients and their families, to communicate with them clearly and to openly develop medicines that transform their lives.

OUR TEAM
tcolasin
Tony Colasin
CBO, Co-Founder
CReyes
Chris Reyes, PhD
CEO, Co-Founder
EHsiao
Elaine Hsiao, PhD
Co-Founder

Our Scientific Advisory Board

JFrench
Jacqueline French, MD

NYU Professor, Department of Neurology

 CSO Epilepsy Foundation

 

DLowenstein
Daniel Lowenstein, MD

UCSF Executive Vice Chancellor and Provost,

Director of UCSF Epilepsy Center

 

EMayer
Emeran Mayer, MD, PhD

UCLA Professor, Physiology and Psychiatry

Director of Oppenheimer Center for Neurobiology,

Author of “The Mind-Gut Connection”

Eric Kossoff
Eric H. Kossoff, MD

Johns Hopkins University Professor, Neurology and Pediatrics

Medical Director of Pediatric Ketogenic Diet Center,

Co-author of “The
Ketogenic and Modified Atkins Diets: Treatments for Epilepsy and Other Disorders”

Jeff Bland
Jeffrey Bland, PhD

CEO Kindex Pharmaceutics

Founder Metagenics

Member, Board of Directors, Board for Certification of Nutrition Specialists

 

Join Us

Sign up to join us on our mission, learn more and for the latest Bloom Science news

Recent news and press

Does Parkinson’s Begin in the Gut?

Efficacy and safety of ketogenic diet for treatment of pediatric convulsive refractory status epilepticus

How bacteria are changing your mood

Interactions between the microbiota, immune and nervous systems in health and disease

We’re on a mission to provide a new solution to the 70 million people that are living with epilepsy.

Contact Us

For general inquiries contact:
info@bloomscience.co